Journal of Clinical and Preventive Cardiology

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 7  |  Issue : 3  |  Page : 86--92

Association of depression, anxiety, and stress with myocardial infarction: A case–control study


MT Manoj1, KA Joseph2, Govindan Vijayaraghavan4 
1 Research and Development Centre, Bharathiar University, Coimbatore, Tamil Nadu; Department of Post Graduate Studies and Cardiology, Kerala Institute of Medical Sciences, Trivandrum, Kerala, India
2 Department of Social Work, Loyola College of Social Sciences, Trivandrum, Kerala, India

Correspondence Address:
Mr. M T Manoj
Kims Hospital, Anayara PO, Trivandrum - 695 029, Kerala
India

Background: Myocardial infarction (MI), the most common cardiovascular disease, has assumed an epidemic proportion today. Higher prevalence of MI is reported from India (a low-middle income country) with the state of Kerala topping the list. Limited data exist on the impact of psychosocial factors on MI in India. Materials and Methods: A total of 100 cases (with MI) and 100 controls (without MI and matched for age and gender) were selected using consecutive sampling from a tertiary hospital in Trivandrum, Kerala, India. Data on depression, anxiety and stress were collected using the depression, anxiety and stress scales (DASS 21). Chi-square test was used to study the association of the variables under study with MI. Multivariate logistic regression was used to control for confounders. The unadjusted and adjusted odds ratios (OR) and 99% confidence intervals (CI) were estimated. Results: Depression (35% vs. 20%, P = 0.024), anxiety (41% vs. 14%, P < 0.001) and stress (36% vs. 15%, P = 0.002) had a statistically significant association with MI on comparing cases vs. controls. Higher levels of depression, anxiety and stress were associated with an increased risk of MI with OR of 2.790, 6.429, and 3.470, respectively. Conclusion: Depression, anxiety and stress were associated with MI. Prospective studies are required to confirm our findings.


How to cite this article:
Manoj M T, Joseph K A, Vijayaraghavan G. Association of depression, anxiety, and stress with myocardial infarction: A case–control study.J Clin Prev Cardiol 2018;7:86-92


How to cite this URL:
Manoj M T, Joseph K A, Vijayaraghavan G. Association of depression, anxiety, and stress with myocardial infarction: A case–control study. J Clin Prev Cardiol [serial online] 2018 [cited 2020 Oct 30 ];7:86-92
Available from: https://www.jcpconline.org/article.asp?issn=2250-3528;year=2018;volume=7;issue=3;spage=86;epage=92;aulast=Manoj;type=0